The groundbreaking research from the University of Georgia on CMX-2043, a potential drug that may help the brain heal after traumatic brain injury (TBI).
It is being reported that researchers from the University of Georgia have discovered a new experimental drug that has the potential to directly repair the brain following a TBI.
This drug is at an early stage of development but it is hoped that it could potentially help the human brain heal by helping cells fight off damage.
The drug, based on a natural antioxidant, is known as ‘CMX-2043 and was initially tested on animals. It acts by increasing enzymes to destroy damaged molecules within the brain. When the brain’s antioxidant defences were stronger, the damage shown on MRI scans was lower.
The researchers are now exploring how the drug may help in human TBI treatment. MRI scans are being used to track responses in real time.
For more information, the study published is Stephanie T. Dubrof et al, Catalase Activity in the Brain Is Associated with Recovery from Brain Injury in a Piglet Model of Traumatic Brain Injury, Brain Sciences (2025). DOI: 10.3390/brainsci15060608.
